Dr. William Heberden, a London physician, described the first cases of Henoch- Schönlein purpura (HSP) in In describing HSP, Heberden wrote of a. Henoch-Schönlein purpura (HSP) affects the blood vessels and causes a spotty rash. It’s not usually serious, but can sometimes lead to kidney problems. Henoch–Schönlein purpura (HSP) is a disease of the skin, mucous membranes, and sometimes other organs that most commonly affects children. In the skin.

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Usually the disease stops re-occurring as patients get older. Any kidney problems usually get better without treatment.

Emotional and mental wellbeing. If your child has Henoch-Schonlein purpura, you may first notice a rash. Most common vasculitis of childhood. So, if your child has a fever with this rash, call an ambulance. These checks should go on for at least 6 months and some doctors recommend a blood pressure and urine check every year for life.

Featured Normal sleep patterns. Steroids, however, do not appear to improve the rash; although usually, over weeks to months, the recurrent bouts of purpura usually resolve on their own.

Evidence of worsening kidney damage would normally prompt a kidney biopsy. Your doctor may recommend a drug called prednisolone. Half the children affected are under the age of five. HSP involves the skin and connective tissues, scrotum, joints, gastrointestinal tract and kidneys.


You’ll usually be asked to provide a sample of pee and have your blood pressure checked at each appointment. What are the symptoms of HSP? Eating, Diet, and Nutrition Eating, diet, and nutrition have not been shown to play a role in causing or preventing HSP.

Henoch-Schonlein purpura | Kidshealth

Adults with severe, acute kidney failure are treated with high-dose corticosteroids and the immunosuppressive cyclophosphamide Cytoxan.

Medical care is generally needed if the disorder affects the kidneys.

In two-thirds of the cases, the disease follows an upper respiratory tract infection, with onset an average of ten days after the start of respiratory symptoms.

In the skin, the disease causes palpable purpura small, raised areas of bleeding underneath the skin asalah, often with joint pain and abdominal pain. The rash does not disappear or turn pale when pressed.

About Vasculitis

Your doctor may order blood tests to exclude other conditions. But recurrences are fairly common. Interventions for preventing and treating kidney disease in Henoch-Schonlein purpura. Patches on prpura dipstick change color when blood or protein are present in urine.

Amiodarone for abnormal heart rhythms. Henoch-Schonlein purpura can also cause abdominal pain and aching joints. Hench of patients and review of the literature”. The kidney tissue is examined in a lab by a pathologist.

The NIDDK translates and disseminates research findings through its clearinghouses and education programs to increase knowledge and understanding about health and disease among patients, health professionals, and the public. There is no specific laboratory test for the disease. Proposal of an international consensus conference”. Leaking blood vessels in the skin cause a rash that looks like bruises or small red dots on the legs, arms, and buttocks.


In adults, kidney involvement progresses to end-stage kidney disease ESKD more often than in children. If you can’t speak to your GP and don’t know what to do next. Systemic lupus erythematosus Subacute bacterial endocarditis Rheumatoid arthritis. HSP occurs more often in children than in adults, [21] and usually follows an upper respiratory tract infection.

Most cases resolve with symptomatic treatment.

Back to Health A-Z. For information on other drugs used in the treatment of vasculitis see Glossary of drugs and side effects.

Fetal alcohol spectrum disorder. Clinical trials look at new ways to prevent, detect, or treat disease. Important You can get HSP more than once. Supportive care may involve a short course of prednisone or an NSAID, such henocj naprosyn or ibuprofen, if the kidneys are not involved.

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