Intoxicación por paraquat: descripción de un caso clínico Paraquat poisoning: a Este es el primer caso humano descrito, ocasionado por un T. pallidus. que habían desarrollado los roedores a los raticidas hasta entonces existentes1.

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A patient who developed an adult respiratory distress syndrome ARDS secondary to deliberate ingestion of paraquat is presented. In both the short and long-term exposure studies, increased corticosterone and altered hippocampal glucocorticoid receptor GR levels were induced by paraquatbut surprisingly these effects were blunted in the older mice.

Using PC12 cells overexpressing a fluorescent protein fused to the proteasome degradation signal, we report here that paraquat yielded an inhibitory effect on 26S proteasome activity without an obvious decline in 20S proteasome activity. The chest CT image of lung injury in 6 cases of paraquat poisoning were analyzed retrospectively.

Goosegrass Eleusine indica L. Honey bee Apis mellifera L. At baseline, there were differences between the H67D HFE mice gumanos WT mice in gut microbiome profile and increased L-ferritin staining in the substantia nigra that could account for the resistance to paraquat.

Transcriptome profiling to discover putative genes associated with paraquat resistance in goosegrass Eleusine indica L. We evaluated their radiographic findings and the differences in imaging features based on mortality. Full Text Available The annual suicide rate in South Korea is the highest among the developed countries.

This is thought to be due to oxidative stress resulting from the generation of cytotoxic reactive oxygen intermediates ROI during paraquat redox cycling.


A year-old male patient was admitted in our department 14 h after paraquat poisoning at the dose of about 50 mL.

As compared to most pesticides, paraquat is extremely toxic to raticiddas and the lack of strategies to manage paraquat poisoning has resulted in high fatality rates. On contrary, median TL values did not correlate with paraquat concentration irrespectively of the exposure protocol.

The biochemical indexes were monitored during the therapy.

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Because paraquat is highly toxic to humans and animals, there is interest in mitigating the consequences of its use, namely by implementing pod procedures capable of curbing its environmental and health risks. The employment of a purpose-made capillary electrophoresis CE instrument with capacitively coupled contactless conductivity detection C 4 D as a simple and cost-effective solution for clinical screening of paraquat in plasma samples for early-stage diagnosis of acute herbicide poisoning is reported.

To investigate the clinical effect of compound monoammonium glycyrrhizinate combined with dandelion in the treatment of acute paraquat poisoning. Wld S also slowed down the death of mice induced by intraperitoneal injection of paraquat.

However, PM was anticipated by two days and harvesting by four days. NLRP3 inflammasome and cytokines secretion in macrophage exposed to paraquat at 24h were measured via immunofluorescence microscopy, western blot or Elisa.

Possible reason of this discrepancy in light of intoxicaccion toxicity is discussed. In contrast, expression of GSTA was significantly greater in differentiated relative to undifferentiated cells after paraquat treatment. In the same patients, follow-up CT scans showed that some areas of focal consolidation could not be visualized and the radio-opacity of the lesions had decreased. The levels of intracellular reactive oxygen species, GSH-Px, SOD, and lipid peroxidation product malondialdehyde were measured to evaluate the oxidative effect of paraquat.


The obtained detection limits were 7. This difference was also shown by using [ 14 C] paraquat. To determine the standing of mortality by poisoning in children.

envenenamiento por paraquat: Topics by

From a comparative viewpoint, lungs of nestling kestrels ratocidas less sensitive to paraquat than mammalian lungs. No residues of bipiridyls were detected, sensitivity less than 0.

Despite increased paraquat entry into raticjdas brain, we could find no evidence for paraquat -induced neuronal cell damage following a detailed histopathological examination of perfused-fixed brains. The clinical pathology process of paraquat poisoning was in line with CT finding which was related with clinical stage and was helpful for clinical assessment of paraquat poisoning promptly and to guide the clinical treatment.

O peso de 1. The damage increased with time of exposure 0, 5, 15, and 30 min following in vitro application, but decreased in longer interval 3 vs 24 h after in vivo administration of paraquat. Paraquat administration in Drosophila for use in metabolic studies of oxidative stress.

A total of 40 taxa were determined. The analytical applicability of proposed method was demonstrated by analyzing water samples from different procedence. Renal function, namely creatinine clearance, was the most significant covariate to explain between patient variability in paraquat clearance.

However, minimal changes such as mild congestion. The adsorption isotherm was found to correspond with Langmuir Isotherm and the maximum paraquat adsorption is Published by Elsevier B.

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